Cargando…

siRNAs targeting the ERK2 signaling pathway and AML1/MTG8 fusion gene attenuate the differentiation, proliferation and growth arrest in t(8;21) leukemia

Detalles Bibliográficos
Autores principales:	Bashanfer, Salem, Al-Hassan, Faisal Mutee, Hassan, Rosline, Heidenreich, Olaf, Mohamed Said, Mohamed Saifulaman, Mohd Yusoff, Narazah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Poster Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467469/ http://dx.doi.org/10.1186/1753-6561-6-S6-P29

Ejemplares similares

A new inducible model for t(8;21) AML
por: Mulloy, James C
Publicado: (2013)

Induction of apoptosis in myeloid leukaemic cells by ribozymes targeted against AML1/MTG8
por: Matsushita, H, et al.
Publicado: (1999)

Identification of a Dynamic Core Transcriptional Network in t(8;21) AML that Regulates Differentiation Block and Self-Renewal
por: Ptasinska, Anetta, et al.
Publicado: (2014)

RUNX1-ETO and RUNX1-EVI1 Differentially Reprogram the Chromatin Landscape in t(8;21) and t(3;21) AML
por: Loke, Justin, et al.
Publicado: (2017)

t(8;21) Acute Myeloid Leukemia as a Paradigm for the Understanding of Leukemogenesis at the Level of Gene Regulation and Chromatin Programming
por: Kellaway, Sophie, et al.
Publicado: (2020)

Chidamide inhibits t(8;21) AML cell proliferation and AMK1/ETO and C-KIT expression by inhibiting ERK1/2 signaling pathway
por: Liu, Jing, et al.
Publicado: (2020)

Clinical, Cytogenetic, and Molecular Findings in Two Cases of Variant t(8;21) Acute Myeloid Leukemia (AML)
por: Wilde, Lindsay, et al.
Publicado: (2019)

LYL1 facilitates AETFC assembly and gene activation by recruiting CARM1 in t(8;21) AML
por: Chen, Qian, et al.
Publicado: (2022)

Genome-wide co-occupancy of AML1-ETO and N-CoR defines the t(8;21) AML signature in leukemic cells
por: Trombly, Daniel J, et al.
Publicado: (2015)

An introduction to the MTG.
por: Lewis, J
Publicado: (1992)

Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding
por: Ptasinska, A, et al.
Publicado: (2012)

Somatic mutational landscape of AML with inv(16) or t(8;21) identifies patterns of clonal evolution in relapse leukemia
por: Sood, Raman, et al.
Publicado: (2015)

Up-regulation of BAALC gene may be an important alteration in AML-M2 patients with t(8;21) translocation
por: Qi, Xiaofei, et al.
Publicado: (2008)

Outcome and prognostic factors of CBF pediatric AML patients with t(8;21) differ from patients with inv(16)
por: Qiu, Kun-yin, et al.
Publicado: (2023)

MicroRNA let-7b downregulates AML1-ETO oncogene expression in t(8;21) AML by targeting its 3′UTR
por: Johnson, Daniel T., et al.
Publicado: (2021)

MTG8 interacts with LHX6 to specify cortical interneuron subtype identity
por: Asgarian, Zeinab, et al.
Publicado: (2022)

The Transcription Co-Repressors MTG8 and MTG16 Regulate Exit of Intestinal Stem Cells From Their Niche and Differentiation Into Enterocyte vs Secretory Lineages
por: Baulies, Anna, et al.
Publicado: (2020)

Celastrol Induces Cell Apoptosis and Inhibits the Expression of the AML1-ETO/C-KIT Oncoprotein in t(8;21) Leukemia
por: Yu, Xianjun, et al.
Publicado: (2016)

Successful Outcome of a Case of Acute Myeloid Leukemia with t(8;21)/AML-ETO Following Langerhans Cell Histiocytosis
por: Meng, Guangqiang, et al.
Publicado: (2019)

Nanoparticle-mediated targeting of the fusion gene RUNX1/ETO in t(8;21)-positive acute myeloid leukaemia
por: Issa, Hasan, et al.
Publicado: (2023)

The RUNX1-ETO target gene RASSF2 suppresses t(8;21) AML development and regulates Rac GTPase signaling
por: Stoner, Samuel A., et al.
Publicado: (2020)

P437: EFFECTIVE IMMUNOTHERAPY OF PEDIATRIC T(8;21) ACUTE MYELOID LEUKEMIA BY REPURPOSING CD3XCD19 TARGETING BISPECIFIC ANTIBODIES
por: Wijnen, Noa, et al.
Publicado: (2023)

A novel epigenetic AML1‐ETO/THAP10/miR‐383 mini‐circuitry contributes to t(8;21) leukaemogenesis
por: Li, Yonghui, et al.
Publicado: (2017)

Peptide microarray profiling identifies phospholipase C gamma 1 (PLC-γ1) as a potential target for t(8;21) AML
por: Mahmud, Hasan, et al.
Publicado: (2017)

The ATRA-21 gene-expression model predicts retinoid sensitivity in CEBPA double mutant, t(8;21) and inv(16) AML patients
por: Bolis, Marco, et al.
Publicado: (2019)

The oncogenic fusion protein RUNX1-CBFA2T1 supports proliferation and inhibits senescence in t(8;21)-positive leukaemic cells
por: Martinez, Natalia, et al.
Publicado: (2004)

Synergistic suppression of t(8;21)-positive leukemia cell growth by combining oridonin and MAPK1/ERK2 inhibitors
por: Spirin, Pavel, et al.
Publicado: (2017)

Epigenetic silencing of UBXN8 contributes to leukemogenesis in t(8;21) acute myeloid leukemia
por: Yang, Erna, et al.
Publicado: (2021)

MiR-130a is aberrantly overexpressed in adult acute myeloid leukemia with t(8;21) and its suppression induces AML cell death
por: Ding, Chao, et al.
Publicado: (2018)

RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction
por: Ptasinska, Anetta, et al.
Publicado: (2019)

RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction
por: Ptasinska, Anetta, et al.
Publicado: (2019)

A Novel Platform to Test In Vivo Single Gene Dependencies in t(8,21) and t(15,17) AML Confirms Zeb2 as Leukemia Target
por: De Conti, Giulia, et al.
Publicado: (2020)

JAK inhibitors suppress t(8;21) fusion protein-induced leukemia
por: Lo, Miao-Chia, et al.
Publicado: (2013)

我如何治疗t（8；21）急性髓系白血病
Publicado: (2017)

Functional and clinical characterization of the alternatively spliced isoform AML1-ETO9a in adult patients with translocation t(8;21)(q22;q22.1) acute myeloid leukemia (AML)
por: Agrawal, Mridul, et al.
Publicado: (2019)

Homoharringtonine combined with aclarubicin and cytarabine synergistically induces apoptosis in t(8;21) leukemia cells and triggers caspase‐3‐mediated cleavage of the AML1‐ETO oncoprotein
por: Cao, Jiang, et al.
Publicado: (2016)

Acute Myeloid Leukemia with the t(8;21) Translocation: Clinical Consequences and Biological Implications
por: Reikvam, Håkon, et al.
Publicado: (2011)

Translocation (8;21) acute myeloid leukemia presenting as severe aplastic anemia
por: Purev, Enkhtsetseg, et al.
Publicado: (2014)

ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation
por: Hartmann, Luise, et al.
Publicado: (2016)

Modelling t(8;21) acute myeloid leukaemia ‐ What have we learned?
por: Chin, Paulynn Suyin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_16msb2qgu5fd4lshh9oqvqqii5