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Molecular mechanisms of genetic variation and transcriptional regulation of CYP2C19

Inherited variation in the function of the drug metabolizing enzyme CYP2C19 was first observed 40 years ago. The SNP variants which underpin loss of CYP2C19 function have been elucidated and extensively studied in healthy populations. However, there has been relatively meagre translation of this inf...

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Detalles Bibliográficos
Autores principales:	Helsby, Nuala Ann, Burns, Kathryn Elisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2012
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467616/ https://www.ncbi.nlm.nih.gov/pubmed/23087703 http://dx.doi.org/10.3389/fgene.2012.00206

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