Method optimization of ocular patches

The intraocular patches were prepared using gelatin as the polymer. Ocular patch were prepared by solvent casting method. The patches were prepared for six formulations GP1, GP2, GP3, GP4, GP5 and GP6. Petri dishes were used for formulation of ocular patch. Gelatin was used as a polymer of choice. G...

Descripción completa

Detalles Bibliográficos
Autores principales: Upreti, Kamalesh, Dabral, Prashant, Rana, Vinod, Upadhyaya, Kumud, Badhani, Anjali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Original/Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467809/
https://www.ncbi.nlm.nih.gov/pubmed/23066196
http://dx.doi.org/10.4103/0975-7406.94130
_version_ 1782245874747834368
author Upreti, Kamalesh
Dabral, Prashant
Rana, Vinod
Upadhyaya, Kumud
Badhani, Anjali
author_facet Upreti, Kamalesh
Dabral, Prashant
Rana, Vinod
Upadhyaya, Kumud
Badhani, Anjali
author_sort Upreti, Kamalesh
collection PubMed
description The intraocular patches were prepared using gelatin as the polymer. Ocular patch were prepared by solvent casting method. The patches were prepared for six formulations GP1, GP2, GP3, GP4, GP5 and GP6. Petri dishes were used for formulation of ocular patch. Gelatin was used as a polymer of choice. Glutaraldehyde used as cross linking agent and (DMSO) dimethylsulfoxide used as solubility enhancer. The elasticity depends upon the concentration of gelatin. 400 mg amount of polymer i.e gelatin gave the required elasticity for the formulation.
format Online
Article
Text
id pubmed-3467809
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-34678092012-10-12 Method optimization of ocular patches Upreti, Kamalesh Dabral, Prashant Rana, Vinod Upadhyaya, Kumud Badhani, Anjali J Pharm Bioallied Sci Original/Brief The intraocular patches were prepared using gelatin as the polymer. Ocular patch were prepared by solvent casting method. The patches were prepared for six formulations GP1, GP2, GP3, GP4, GP5 and GP6. Petri dishes were used for formulation of ocular patch. Gelatin was used as a polymer of choice. Glutaraldehyde used as cross linking agent and (DMSO) dimethylsulfoxide used as solubility enhancer. The elasticity depends upon the concentration of gelatin. 400 mg amount of polymer i.e gelatin gave the required elasticity for the formulation. Medknow Publications & Media Pvt Ltd 2012-03 /pmc/articles/PMC3467809/ /pubmed/23066196 http://dx.doi.org/10.4103/0975-7406.94130 Text en Copyright: © Journal of Pharmacy and Bioallied Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original/Brief
Upreti, Kamalesh
Dabral, Prashant
Rana, Vinod
Upadhyaya, Kumud
Badhani, Anjali
Method optimization of ocular patches
title Method optimization of ocular patches
title_full Method optimization of ocular patches
title_fullStr Method optimization of ocular patches
title_full_unstemmed Method optimization of ocular patches
title_short Method optimization of ocular patches
title_sort method optimization of ocular patches
topic Original/Brief
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467809/
https://www.ncbi.nlm.nih.gov/pubmed/23066196
http://dx.doi.org/10.4103/0975-7406.94130
work_keys_str_mv AT upretikamalesh methodoptimizationofocularpatches
AT dabralprashant methodoptimizationofocularpatches
AT ranavinod methodoptimizationofocularpatches
AT upadhyayakumud methodoptimizationofocularpatches
AT badhanianjali methodoptimizationofocularpatches

Ejemplares similares