Design and development of colon specific microspheres for chronotherapy of hypertension

The purpose of this research was to design, and evaluate multiparticulate systems for Chronotherapeutic delivery of beta blocker containing biodegradable polymers coated with pH sensitive polymers in hypertension. Chitosan was used as a carrier for drug delivery and Eudragit S100 was used as an ente...

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Detalles Bibliográficos
Autores principales: Patel, P., Dhake, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Original/Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467814/
https://www.ncbi.nlm.nih.gov/pubmed/23066197
http://dx.doi.org/10.4103/0975-7406.94132
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author Patel, P.
Dhake, A.
author_facet Patel, P.
Dhake, A.
author_sort Patel, P.
collection PubMed
description The purpose of this research was to design, and evaluate multiparticulate systems for Chronotherapeutic delivery of beta blocker containing biodegradable polymers coated with pH sensitive polymers in hypertension. Chitosan was used as a carrier for drug delivery and Eudragit S100 was used as an enteric coating polymer. 3(2) full factorial design was employed to optimize the proper formulation for Chronotherapeutic drug delivery.
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spelling pubmed-34678142012-10-12 Design and development of colon specific microspheres for chronotherapy of hypertension Patel, P. Dhake, A. J Pharm Bioallied Sci Original/Brief The purpose of this research was to design, and evaluate multiparticulate systems for Chronotherapeutic delivery of beta blocker containing biodegradable polymers coated with pH sensitive polymers in hypertension. Chitosan was used as a carrier for drug delivery and Eudragit S100 was used as an enteric coating polymer. 3(2) full factorial design was employed to optimize the proper formulation for Chronotherapeutic drug delivery. Medknow Publications & Media Pvt Ltd 2012-03 /pmc/articles/PMC3467814/ /pubmed/23066197 http://dx.doi.org/10.4103/0975-7406.94132 Text en Copyright: © Journal of Pharmacy and Bioallied Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original/Brief
Patel, P.
Dhake, A.
Design and development of colon specific microspheres for chronotherapy of hypertension
title Design and development of colon specific microspheres for chronotherapy of hypertension
title_full Design and development of colon specific microspheres for chronotherapy of hypertension
title_fullStr Design and development of colon specific microspheres for chronotherapy of hypertension
title_full_unstemmed Design and development of colon specific microspheres for chronotherapy of hypertension
title_short Design and development of colon specific microspheres for chronotherapy of hypertension
title_sort design and development of colon specific microspheres for chronotherapy of hypertension
topic Original/Brief
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467814/
https://www.ncbi.nlm.nih.gov/pubmed/23066197
http://dx.doi.org/10.4103/0975-7406.94132
work_keys_str_mv AT patelp designanddevelopmentofcolonspecificmicrospheresforchronotherapyofhypertension
AT dhakea designanddevelopmentofcolonspecificmicrospheresforchronotherapyofhypertension

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