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Solubility enhancement of benfotiamine, a lipid derivative of thiamine by solid dispersion technique

The present study was aimed to increase the solubility of the poorly water soluble drug benfotiamine using hydrophilic polymers (PVP K-30 and HPMC E4). Solid dispersions were prepared by kneading method. Phase solubility study, in-vitro dissolution of pure drug, physical mixtures and solid dispersio...

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Detalles Bibliográficos
Autores principales:	Patel, S. M., Patel, R. P., Prajapati, B. G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2012
Materias:	Original/Brief
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467834/ https://www.ncbi.nlm.nih.gov/pubmed/23066179 http://dx.doi.org/10.4103/0975-7406.94157

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