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Preparation and formulation of transferosomes containing an antifungal agent for transdermal delivery: Application of Plackett-Burman design to identify significant factors influencing vesicle size
Transferosomes containing an anti-fungal agent were prepared by Rotary Flask Evaporation –Sonication method. Eight batches were prepared in triplicate and vesicle size of each batch was determined. Plackett-Burman Design was employed to identify significant formulation and process parameters affecti...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467850/ https://www.ncbi.nlm.nih.gov/pubmed/23066209 http://dx.doi.org/10.4103/0975-7406.94140 |
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author | Patel, Rutu B. Parikh, R. H. |
author_facet | Patel, Rutu B. Parikh, R. H. |
author_sort | Patel, Rutu B. |
collection | PubMed |
description | Transferosomes containing an anti-fungal agent were prepared by Rotary Flask Evaporation –Sonication method. Eight batches were prepared in triplicate and vesicle size of each batch was determined. Plackett-Burman Design was employed to identify significant formulation and process parameters affecting vesicle size. The amount of lipid and surfactant, volume of ethanol and hydration medium as well as hydration time significantly affect the vesicle size. |
format | Online Article Text |
id | pubmed-3467850 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-34678502012-10-12 Preparation and formulation of transferosomes containing an antifungal agent for transdermal delivery: Application of Plackett-Burman design to identify significant factors influencing vesicle size Patel, Rutu B. Parikh, R. H. J Pharm Bioallied Sci Original/Brief Transferosomes containing an anti-fungal agent were prepared by Rotary Flask Evaporation –Sonication method. Eight batches were prepared in triplicate and vesicle size of each batch was determined. Plackett-Burman Design was employed to identify significant formulation and process parameters affecting vesicle size. The amount of lipid and surfactant, volume of ethanol and hydration medium as well as hydration time significantly affect the vesicle size. Medknow Publications & Media Pvt Ltd 2012-03 /pmc/articles/PMC3467850/ /pubmed/23066209 http://dx.doi.org/10.4103/0975-7406.94140 Text en Copyright: © Journal of Pharmacy and Bioallied Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original/Brief Patel, Rutu B. Parikh, R. H. Preparation and formulation of transferosomes containing an antifungal agent for transdermal delivery: Application of Plackett-Burman design to identify significant factors influencing vesicle size |
title | Preparation and formulation of transferosomes containing an antifungal agent for transdermal delivery: Application of Plackett-Burman design to identify significant factors influencing vesicle size |
title_full | Preparation and formulation of transferosomes containing an antifungal agent for transdermal delivery: Application of Plackett-Burman design to identify significant factors influencing vesicle size |
title_fullStr | Preparation and formulation of transferosomes containing an antifungal agent for transdermal delivery: Application of Plackett-Burman design to identify significant factors influencing vesicle size |
title_full_unstemmed | Preparation and formulation of transferosomes containing an antifungal agent for transdermal delivery: Application of Plackett-Burman design to identify significant factors influencing vesicle size |
title_short | Preparation and formulation of transferosomes containing an antifungal agent for transdermal delivery: Application of Plackett-Burman design to identify significant factors influencing vesicle size |
title_sort | preparation and formulation of transferosomes containing an antifungal agent for transdermal delivery: application of plackett-burman design to identify significant factors influencing vesicle size |
topic | Original/Brief |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467850/ https://www.ncbi.nlm.nih.gov/pubmed/23066209 http://dx.doi.org/10.4103/0975-7406.94140 |
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