Preparation, optimization and characterization of multiple unit microspheres containing kollidone SR

The present investigation described the influence of viscosity and drug: Polymer ratio on Hydrochlorothiazide release. Floating microspheres loaded with hydrochlorothiazide were prepared by Emulsion solvent evaporation method. The prepared microspheres were evaluated by micromeritics properties, in...

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Detalles Bibliográficos
Autores principales: Patel, Marvin I., Patel, Ravi R., Patel, Jayvadan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Original/Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467853/
https://www.ncbi.nlm.nih.gov/pubmed/23066219
http://dx.doi.org/10.4103/0975-7406.94149
Descripción
Sumario:The present investigation described the influence of viscosity and drug: Polymer ratio on Hydrochlorothiazide release. Floating microspheres loaded with hydrochlorothiazide were prepared by Emulsion solvent evaporation method. The prepared microspheres were evaluated by micromeritics properties, in vitro drug release, floating ability and drug entrapment efficiency.

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