The effects of weekly augmentation therapy in patients with PiZZ α1-antitrypsin deficiency

BACKGROUND: The major concept behind augmentation therapy with human α(1)-antitrypsin (AAT) is to raise the levels of AAT in patients with protease inhibitor phenotype ZZ (Glu342Lys)-inherited AAT deficiency and to protect lung tissues from proteolysis and progression of emphysema. OBJECTIVE: To eva...

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Detalles Bibliográficos
Autores principales: Schmid, ST, Koepke, J, Dresel, M, Hattesohl, A, Frenzel, E, Perez, J, Lomas, DA, Miranda, E, Greulich, T, Noeske, S, Wencker, M, Teschler, H, Vogelmeier, C, Janciauskiene, S, Koczulla, AR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468059/
https://www.ncbi.nlm.nih.gov/pubmed/23055718
http://dx.doi.org/10.2147/COPD.S34560

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