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Computational analysis of calcium signaling and membrane electrophysiology in cerebellar Purkinje neurons associated with ataxia

BACKGROUND: Mutations in the smooth endoplasmic reticulum (sER) calcium channel Inositol Trisphosphate Receptor type 1 (IP3R1) in humans with the motor function coordination disorders Spinocerebellar Ataxia Types 15 and 16 (SCA15/16) and in a corresponding mouse model, the IP3R1(delta18/delta18) mic...

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Detalles Bibliográficos
Autores principales:	Brown, Sherry-Ann, Loew, Leslie M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468360/ https://www.ncbi.nlm.nih.gov/pubmed/22703638 http://dx.doi.org/10.1186/1752-0509-6-70

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