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Adoptive Paternal Age and Risk of Psychosis in Adoptees: A Register Based Cohort Study

The association between advancing paternal age and increased risk of schizophrenia in the off-spring is well established. The underlying mechanisms are unknown. In order to investigate whether the psychosocial environment associated with growing up with an aged father explains the increased risk we...

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Detalles Bibliográficos
Autores principales: Ek, Mats, Wicks, Susanne, Magnusson, Cecilia, Dalman, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468435/
https://www.ncbi.nlm.nih.gov/pubmed/23071791
http://dx.doi.org/10.1371/journal.pone.0047334
Descripción
Sumario:The association between advancing paternal age and increased risk of schizophrenia in the off-spring is well established. The underlying mechanisms are unknown. In order to investigate whether the psychosocial environment associated with growing up with an aged father explains the increased risk we conducted a study of all adoptive children in Sweden from 1955–1985 (n = 31 188). Their risk of developing schizophrenia or non-affective psychosis in relation to advancing age of their adoptive fathers’ was examined. We found no association between risk of psychoses and advancing adoptive paternal age. There was no support of psychosocial environmental factors explaining the “paternal age effect”.