Adoptive Paternal Age and Risk of Psychosis in Adoptees: A Register Based Cohort Study

The association between advancing paternal age and increased risk of schizophrenia in the off-spring is well established. The underlying mechanisms are unknown. In order to investigate whether the psychosocial environment associated with growing up with an aged father explains the increased risk we...

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Detalles Bibliográficos
Autores principales: Ek, Mats, Wicks, Susanne, Magnusson, Cecilia, Dalman, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468435/
https://www.ncbi.nlm.nih.gov/pubmed/23071791
http://dx.doi.org/10.1371/journal.pone.0047334
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author Ek, Mats
Wicks, Susanne
Magnusson, Cecilia
Dalman, Christina
author_facet Ek, Mats
Wicks, Susanne
Magnusson, Cecilia
Dalman, Christina
author_sort Ek, Mats
collection PubMed
description The association between advancing paternal age and increased risk of schizophrenia in the off-spring is well established. The underlying mechanisms are unknown. In order to investigate whether the psychosocial environment associated with growing up with an aged father explains the increased risk we conducted a study of all adoptive children in Sweden from 1955–1985 (n = 31 188). Their risk of developing schizophrenia or non-affective psychosis in relation to advancing age of their adoptive fathers’ was examined. We found no association between risk of psychoses and advancing adoptive paternal age. There was no support of psychosocial environmental factors explaining the “paternal age effect”.
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spelling pubmed-34684352012-10-15 Adoptive Paternal Age and Risk of Psychosis in Adoptees: A Register Based Cohort Study Ek, Mats Wicks, Susanne Magnusson, Cecilia Dalman, Christina PLoS One Research Article The association between advancing paternal age and increased risk of schizophrenia in the off-spring is well established. The underlying mechanisms are unknown. In order to investigate whether the psychosocial environment associated with growing up with an aged father explains the increased risk we conducted a study of all adoptive children in Sweden from 1955–1985 (n = 31 188). Their risk of developing schizophrenia or non-affective psychosis in relation to advancing age of their adoptive fathers’ was examined. We found no association between risk of psychoses and advancing adoptive paternal age. There was no support of psychosocial environmental factors explaining the “paternal age effect”. Public Library of Science 2012-10-10 /pmc/articles/PMC3468435/ /pubmed/23071791 http://dx.doi.org/10.1371/journal.pone.0047334 Text en © 2012 Ek et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Ek, Mats
Wicks, Susanne
Magnusson, Cecilia
Dalman, Christina
Adoptive Paternal Age and Risk of Psychosis in Adoptees: A Register Based Cohort Study
title Adoptive Paternal Age and Risk of Psychosis in Adoptees: A Register Based Cohort Study
title_full Adoptive Paternal Age and Risk of Psychosis in Adoptees: A Register Based Cohort Study
title_fullStr Adoptive Paternal Age and Risk of Psychosis in Adoptees: A Register Based Cohort Study
title_full_unstemmed Adoptive Paternal Age and Risk of Psychosis in Adoptees: A Register Based Cohort Study
title_short Adoptive Paternal Age and Risk of Psychosis in Adoptees: A Register Based Cohort Study
title_sort adoptive paternal age and risk of psychosis in adoptees: a register based cohort study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468435/
https://www.ncbi.nlm.nih.gov/pubmed/23071791
http://dx.doi.org/10.1371/journal.pone.0047334
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