Functional Assessment of Human Coding Mutations Affecting Skin Pigmentation Using Zebrafish

A major challenge in personalized medicine is the lack of a standard way to define the functional significance of the numerous nonsynonymous, single nucleotide coding variants that are present in each human individual. To begin to address this problem, we have used pigmentation as a model polygenic...

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Detalles Bibliográficos
Autores principales: Tsetskhladze, Zurab R., Canfield, Victor A., Ang, Khai C., Wentzel, Steven M., Reid, Katherine P., Berg, Arthur S., Johnson, Stephen L., Kawakami, Koichi, Cheng, Keith C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468441/
https://www.ncbi.nlm.nih.gov/pubmed/23071798
http://dx.doi.org/10.1371/journal.pone.0047398

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