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Synergistic Antitumor Effects of Endostar in Combination with Oxaliplatin via Inhibition of HIF and CXCR4 in the Colorectal Cell Line SW1116

Combination treatment with endostar, a novel modified endostatin, and cytotoxic chemotherapies showed a survival benefit in Chinese clinical trials. However, the exact mechanism for this synergism remains unclear. In this study, we report for the first time that the chemokine receptor CXCR4 and the...

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Detalles Bibliográficos
Autores principales:	Jin, Fengyan, Ji, Huifan, Jia, Chunshu, Brockmeier, Ulf, Hermann, Dirk M., Metzen, Eric, Zhu, Yingqiao, Chi, Baorong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468460/ https://www.ncbi.nlm.nih.gov/pubmed/23071744 http://dx.doi.org/10.1371/journal.pone.0047161

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