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Activating Nrf-2 Signaling Depresses Unilateral Ureteral Obstruction-Evoked Mitochondrial Stress-Related Autophagy, Apoptosis and Pyroptosis in Kidney

Exacerbated oxidative stress and inflammation may induce three types of programmed cell death, autophagy, apoptosis and pyroptosis in unilateral ureteral obstruction (UUO) kidney. Sulforaphane activating NF-E2-related nuclear factor erythroid-2 (Nrf-2) signaling may ameliorate UUO-induced renal dama...

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Detalles Bibliográficos
Autores principales: Chung, Shue Dong, Lai, Ting Yu, Chien, Chiang Ting, Yu, Hong Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468574/
https://www.ncbi.nlm.nih.gov/pubmed/23071780
http://dx.doi.org/10.1371/journal.pone.0047299