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Silencing of Glutathione Peroxidase 3 through DNA Hypermethylation Is Associated with Lymph Node Metastasis in Gastric Carcinomas

Gastric cancer remains the second leading cause of cancer-related death in the world. H. pylori infection, a major risk factor for gastric cancer, generates high levels of reactive oxygen species (ROS). Glutathione peroxidase 3 (GPX3), a plasma GPX member and a major scavenger of ROS, catalyzes the...

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Detalles Bibliográficos
Autores principales:	Peng, Dun-Fa, Hu, Tian-Ling, Schneider, Barbara G., Chen, Zheng, Xu, Ze-Kuan, El-Rifai, Wael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468580/ https://www.ncbi.nlm.nih.gov/pubmed/23071548 http://dx.doi.org/10.1371/journal.pone.0046214

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