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Type III Interferons, IL-28 and IL-29, Are Increased in Chronic HCV Infection and Induce Myeloid Dendritic Cell-Mediated FoxP3+ Regulatory T Cells

BACKGROUND & AIMS: Hepatitis C virus (HCV) is difficult to eradicate and type III interferons (IFN-λ, composed of IL-28A, IL-28B and IL-29) are novel therapeutic candidates. We hypothesized that IFN-λ have immunomodulatory effects in HCV- infected individuals. MATERIALS AND METHODS: We analyzed...

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Detalles Bibliográficos
Autores principales:	Dolganiuc, Angela, Kodys, Karen, Marshall, Christopher, Saha, Banishree, Zhang, Shuye, Bala, Shashi, Szabo, Gyongyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468613/ https://www.ncbi.nlm.nih.gov/pubmed/23071503 http://dx.doi.org/10.1371/journal.pone.0044915

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