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Heat shock factor 1 is inactivated by amino acid deprivation
Mammalian cells respond to a lack of amino acids by activating a transcriptional program with the transcription factor ATF4 as one of the main actors. When cells are faced with cytoplasmic proteotoxic stress, a quite different transcriptional response is mounted, the heat shock response, which is me...
Autores principales: | Hensen, Sanne M. M., Heldens, Lonneke, van Enckevort, Chrissy M. W., van Genesen, Siebe T., Pruijn, Ger J. M., Lubsen, Nicolette H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468675/ https://www.ncbi.nlm.nih.gov/pubmed/22797943 http://dx.doi.org/10.1007/s12192-012-0347-1 |
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