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Brain Connectivity Studies in Schizophrenia: Unravelling the Effects of Antipsychotics

Impaired brain connectivity is a hallmark of schizophrenia brain dysfunction. However, the effect of drug treatment and challenges on the dysconnectivity of functional networks in schizophrenia is an understudied area. In this review, we provide an overview of functional magnetic resonance imaging s...

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Detalles Bibliográficos
Autores principales: Nejad, Ayna B, Ebdrup, Bjørn H, Glenthøj, Birte Y, Siebner, Hartwig R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468876/
https://www.ncbi.nlm.nih.gov/pubmed/23449679
http://dx.doi.org/10.2174/157015912803217305
Descripción
Sumario:Impaired brain connectivity is a hallmark of schizophrenia brain dysfunction. However, the effect of drug treatment and challenges on the dysconnectivity of functional networks in schizophrenia is an understudied area. In this review, we provide an overview of functional magnetic resonance imaging studies examining dysconnectivity in schizophrenia and discuss the few studies which have also attempted to probe connectivity changes with antipsychotic drug treatment. We conclude with a discussion of possible avenues for further investigation.