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Prevalence of GBV-C RNA in HIV infected individuals in Tehran, Iran

BACKGROUND: GB virus C (GBV-C) is a flavivirus that was characterized in 1995. The prevalence of GBV-C RNA in HIV-infected subjects has not been previously studied in Iran and was therefore determined. METHODS: We have investigated serum samples of 80 patients from Imam Khomeini Hospital, Tehran, Ir...

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Autores principales: Keyvani, H, Mohammadi, A, Haji-abdolbaghi, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468976/
https://www.ncbi.nlm.nih.gov/pubmed/23112986
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author Keyvani, H
Mohammadi, A
Haji-abdolbaghi, M
author_facet Keyvani, H
Mohammadi, A
Haji-abdolbaghi, M
author_sort Keyvani, H
collection PubMed
description BACKGROUND: GB virus C (GBV-C) is a flavivirus that was characterized in 1995. The prevalence of GBV-C RNA in HIV-infected subjects has not been previously studied in Iran and was therefore determined. METHODS: We have investigated serum samples of 80 patients from Imam Khomeini Hospital, Tehran, Iran, whose HIV infection was confirmed in our laboratory by Western-blotting. We used nested-PCR to detect GBV-C/HGV RNA in their sera. RESULTS: GBV-C/HGV RNA was detected in 15 (18.8%) of 80 patients. There was no significant difference in GBV-C/HGV RNA prevalence between males and females, in different age groups and HIV viral loads groups. CONCLUSION: The prevalence of GBV-C RNA was high in HIV-infected patients. There was no association between GBV-C RNA prevalence and specific gender, age, and HIV viral loads groups.
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spelling pubmed-34689762012-10-30 Prevalence of GBV-C RNA in HIV infected individuals in Tehran, Iran Keyvani, H Mohammadi, A Haji-abdolbaghi, M Iran J Public Health Original Article BACKGROUND: GB virus C (GBV-C) is a flavivirus that was characterized in 1995. The prevalence of GBV-C RNA in HIV-infected subjects has not been previously studied in Iran and was therefore determined. METHODS: We have investigated serum samples of 80 patients from Imam Khomeini Hospital, Tehran, Iran, whose HIV infection was confirmed in our laboratory by Western-blotting. We used nested-PCR to detect GBV-C/HGV RNA in their sera. RESULTS: GBV-C/HGV RNA was detected in 15 (18.8%) of 80 patients. There was no significant difference in GBV-C/HGV RNA prevalence between males and females, in different age groups and HIV viral loads groups. CONCLUSION: The prevalence of GBV-C RNA was high in HIV-infected patients. There was no association between GBV-C RNA prevalence and specific gender, age, and HIV viral loads groups. Tehran University of Medical Sciences 2010-03-31 /pmc/articles/PMC3468976/ /pubmed/23112986 Text en Copyright © Iranian Public Health Association & Tehran University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0), which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Original Article
Keyvani, H
Mohammadi, A
Haji-abdolbaghi, M
Prevalence of GBV-C RNA in HIV infected individuals in Tehran, Iran
title Prevalence of GBV-C RNA in HIV infected individuals in Tehran, Iran
title_full Prevalence of GBV-C RNA in HIV infected individuals in Tehran, Iran
title_fullStr Prevalence of GBV-C RNA in HIV infected individuals in Tehran, Iran
title_full_unstemmed Prevalence of GBV-C RNA in HIV infected individuals in Tehran, Iran
title_short Prevalence of GBV-C RNA in HIV infected individuals in Tehran, Iran
title_sort prevalence of gbv-c rna in hiv infected individuals in tehran, iran
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468976/
https://www.ncbi.nlm.nih.gov/pubmed/23112986
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