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Inhibition of Leishmania major PTR1 Gene Expression by Antisense in Escherichia coli

BACKGROUND: Protozoa related to Trypanosome family including Leishmania, synthesize enzymes to escape from drug therapy. One of them is PTR1 that its enzymatic activity is similar to dihydrofolate reductase (DHFR). Dihydrofolate reductase - thymidylate synthase has a major role in DNA synthesis, if...

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Detalles Bibliográficos
Autores principales:	Kheirandish, F, Bandehpour, M, Haghighi, A, Mahboudi, F, Mohebali, M, Kazemi, B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Tehran University of Medical Sciences 2012
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468993/ https://www.ncbi.nlm.nih.gov/pubmed/23113195

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