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The yeast Hsp70 Ssa1 is a sensor for activation of the heat shock response by thiol-reactive compounds

The heat shock transcription factor HSF1 governs the response to heat shock, oxidative stresses, and xenobiotics through unknown mechanisms. We demonstrate that diverse thiol-reactive molecules potently activate budding yeast Hsf1. Hsf1 activation by thiol-reactive compounds is not consistent with t...

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Detalles Bibliográficos
Autores principales:	Wang, Yanyu, Gibney, Patrick A., West, James D., Morano, Kevin A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469052/ https://www.ncbi.nlm.nih.gov/pubmed/22809627 http://dx.doi.org/10.1091/mbc.E12-06-0447

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