The Effects of Local Administration of Aminophylline on Transureteral Lithotripsy

Introduction. Urinary stone is a common cause of urinary tract disease. Stone excretion using ureteroscope is effective in inferior ureter. The aim of this study was to investigate the effects of aminophylline on ureteral spasm during ureteroscopy in acute phase of renal colic. Methods. In this doub...

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Autores principales: Barzegarnezhad, Ayyoub, Firouzian, Abolfazl, Emadi, Seyed Abdollah, Mousanejad, Nadali, Bakhshali, Roksana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469073/
https://www.ncbi.nlm.nih.gov/pubmed/23082076
http://dx.doi.org/10.1155/2012/727843
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author Barzegarnezhad, Ayyoub
Firouzian, Abolfazl
Emadi, Seyed Abdollah
Mousanejad, Nadali
Bakhshali, Roksana
author_facet Barzegarnezhad, Ayyoub
Firouzian, Abolfazl
Emadi, Seyed Abdollah
Mousanejad, Nadali
Bakhshali, Roksana
author_sort Barzegarnezhad, Ayyoub
collection PubMed
description Introduction. Urinary stone is a common cause of urinary tract disease. Stone excretion using ureteroscope is effective in inferior ureter. The aim of this study was to investigate the effects of aminophylline on ureteral spasm during ureteroscopy in acute phase of renal colic. Methods. In this double-blind randomized clinical trial, 120 patients with ureteral stones were enrolled and randomized into two groups. The bladder was drained and then received a 150 mL irrigation solution. Irrigation solution was saline and saline plus 10 mL aminophylline at 250 mg dose for control and case groups, respectively. Ureteroscopy and transureteral lithotripsy (TUL) were performed five minutes after irrigation. Results. The mean duration of TUL was 4.2 ± 2.61 min and 8.4 ± 2.9 min for control and case groups, respectively. The successful rate was 95% and 76.1% in case and control groups, respectively. Further extracorporeal shock wave lithotripsy (SWL) was performed in 5% and 30% for patients in case and control groups, respectively. Conclusion. Aminophylline facilitated ureteroscopy and increased the success rate in the treatment of renal colic using TUL. No significant complications from post-TUL were observed. Using aminophylline carries several advantages such as reducing procedure duration, decreasing the need for ureteral and double-J catheter, and reducing stone migration to the kidney and use of SWL.
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spelling pubmed-34690732012-10-18 The Effects of Local Administration of Aminophylline on Transureteral Lithotripsy Barzegarnezhad, Ayyoub Firouzian, Abolfazl Emadi, Seyed Abdollah Mousanejad, Nadali Bakhshali, Roksana Adv Urol Clinical Study Introduction. Urinary stone is a common cause of urinary tract disease. Stone excretion using ureteroscope is effective in inferior ureter. The aim of this study was to investigate the effects of aminophylline on ureteral spasm during ureteroscopy in acute phase of renal colic. Methods. In this double-blind randomized clinical trial, 120 patients with ureteral stones were enrolled and randomized into two groups. The bladder was drained and then received a 150 mL irrigation solution. Irrigation solution was saline and saline plus 10 mL aminophylline at 250 mg dose for control and case groups, respectively. Ureteroscopy and transureteral lithotripsy (TUL) were performed five minutes after irrigation. Results. The mean duration of TUL was 4.2 ± 2.61 min and 8.4 ± 2.9 min for control and case groups, respectively. The successful rate was 95% and 76.1% in case and control groups, respectively. Further extracorporeal shock wave lithotripsy (SWL) was performed in 5% and 30% for patients in case and control groups, respectively. Conclusion. Aminophylline facilitated ureteroscopy and increased the success rate in the treatment of renal colic using TUL. No significant complications from post-TUL were observed. Using aminophylline carries several advantages such as reducing procedure duration, decreasing the need for ureteral and double-J catheter, and reducing stone migration to the kidney and use of SWL. Hindawi Publishing Corporation 2012 2012-10-02 /pmc/articles/PMC3469073/ /pubmed/23082076 http://dx.doi.org/10.1155/2012/727843 Text en Copyright © 2012 Ayyoub Barzegarnezhad et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Barzegarnezhad, Ayyoub
Firouzian, Abolfazl
Emadi, Seyed Abdollah
Mousanejad, Nadali
Bakhshali, Roksana
The Effects of Local Administration of Aminophylline on Transureteral Lithotripsy
title The Effects of Local Administration of Aminophylline on Transureteral Lithotripsy
title_full The Effects of Local Administration of Aminophylline on Transureteral Lithotripsy
title_fullStr The Effects of Local Administration of Aminophylline on Transureteral Lithotripsy
title_full_unstemmed The Effects of Local Administration of Aminophylline on Transureteral Lithotripsy
title_short The Effects of Local Administration of Aminophylline on Transureteral Lithotripsy
title_sort effects of local administration of aminophylline on transureteral lithotripsy
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469073/
https://www.ncbi.nlm.nih.gov/pubmed/23082076
http://dx.doi.org/10.1155/2012/727843
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