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Side chain modified peptide nucleic acids (PNA) for knock-down of six3 in medaka embryos
BACKGROUND: Synthetic antisense molecules have an enormous potential for therapeutic applications in humans. The major aim of such strategies is to specifically interfere with gene function, thus modulating cellular pathways according to the therapeutic demands. Among the molecules which can block m...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469332/ https://www.ncbi.nlm.nih.gov/pubmed/22901024 http://dx.doi.org/10.1186/1472-6750-12-50 |