Anemia secondary to valproic acid therapy in a 13-year-old boy: a case report

INTRODUCTION: Valproic acid is a commonly used anti-epileptic drug. Hematological toxicities are among the occasionally observed adverse effects of this medication. CASE PRESENTATION: We present the case of a 13-year-old Caucasian boy who demonstrated mild anemia 12 months after the introduction of...

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Autores principales: Kaczorowska-Hac, Barbara, Matheisel, Agnieszka, Maciejka-Kapuscinska, Lucyna, Wisniewski, Jakub, Alska, Anna, Adamkiewicz-Drozynska, Elzbieta, Balcerska, Anna, Reszczynska, Iwona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469403/
https://www.ncbi.nlm.nih.gov/pubmed/22883745
http://dx.doi.org/10.1186/1752-1947-6-239
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author Kaczorowska-Hac, Barbara
Matheisel, Agnieszka
Maciejka-Kapuscinska, Lucyna
Wisniewski, Jakub
Alska, Anna
Adamkiewicz-Drozynska, Elzbieta
Balcerska, Anna
Reszczynska, Iwona
author_facet Kaczorowska-Hac, Barbara
Matheisel, Agnieszka
Maciejka-Kapuscinska, Lucyna
Wisniewski, Jakub
Alska, Anna
Adamkiewicz-Drozynska, Elzbieta
Balcerska, Anna
Reszczynska, Iwona
author_sort Kaczorowska-Hac, Barbara
collection PubMed
description INTRODUCTION: Valproic acid is a commonly used anti-epileptic drug. Hematological toxicities are among the occasionally observed adverse effects of this medication. CASE PRESENTATION: We present the case of a 13-year-old Caucasian boy who demonstrated mild anemia 12 months after the introduction of valproic acid therapy. A bone marrow biopsy revealed maturation arrest of proerythroblasts. CONCLUSION: Prompt diagnosis and valproic acid discontinuation resulted in the patient’s recovery.
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spelling pubmed-34694032012-10-12 Anemia secondary to valproic acid therapy in a 13-year-old boy: a case report Kaczorowska-Hac, Barbara Matheisel, Agnieszka Maciejka-Kapuscinska, Lucyna Wisniewski, Jakub Alska, Anna Adamkiewicz-Drozynska, Elzbieta Balcerska, Anna Reszczynska, Iwona J Med Case Rep Case Report INTRODUCTION: Valproic acid is a commonly used anti-epileptic drug. Hematological toxicities are among the occasionally observed adverse effects of this medication. CASE PRESENTATION: We present the case of a 13-year-old Caucasian boy who demonstrated mild anemia 12 months after the introduction of valproic acid therapy. A bone marrow biopsy revealed maturation arrest of proerythroblasts. CONCLUSION: Prompt diagnosis and valproic acid discontinuation resulted in the patient’s recovery. BioMed Central 2012-08-10 /pmc/articles/PMC3469403/ /pubmed/22883745 http://dx.doi.org/10.1186/1752-1947-6-239 Text en Copyright ©2012 Kaczorowska-Hac et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kaczorowska-Hac, Barbara
Matheisel, Agnieszka
Maciejka-Kapuscinska, Lucyna
Wisniewski, Jakub
Alska, Anna
Adamkiewicz-Drozynska, Elzbieta
Balcerska, Anna
Reszczynska, Iwona
Anemia secondary to valproic acid therapy in a 13-year-old boy: a case report
title Anemia secondary to valproic acid therapy in a 13-year-old boy: a case report
title_full Anemia secondary to valproic acid therapy in a 13-year-old boy: a case report
title_fullStr Anemia secondary to valproic acid therapy in a 13-year-old boy: a case report
title_full_unstemmed Anemia secondary to valproic acid therapy in a 13-year-old boy: a case report
title_short Anemia secondary to valproic acid therapy in a 13-year-old boy: a case report
title_sort anemia secondary to valproic acid therapy in a 13-year-old boy: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469403/
https://www.ncbi.nlm.nih.gov/pubmed/22883745
http://dx.doi.org/10.1186/1752-1947-6-239
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