Cargando…

The Contribution of RNA Decay Quantitative Trait Loci to Inter-Individual Variation in Steady-State Gene Expression Levels

Recent gene expression QTL (eQTL) mapping studies have provided considerable insight into the genetic basis for inter-individual regulatory variation. However, a limitation of all eQTL studies to date, which have used measurements of steady-state gene expression levels, is the inability to directly...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pai, Athma A., Cain, Carolyn E., Mizrahi-Man, Orna, De Leon, Sherryl, Lewellen, Noah, Veyrieras, Jean-Baptiste, Degner, Jacob F., Gaffney, Daniel J., Pickrell, Joseph K., Stephens, Matthew, Pritchard, Jonathan K., Gilad, Yoav
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469421/ https://www.ncbi.nlm.nih.gov/pubmed/23071454 http://dx.doi.org/10.1371/journal.pgen.1003000

Ejemplares similares

DNaseI sensitivity QTLs are a major determinant of human expression variation
por: Degner, Jacob F., et al.
Publicado: (2012)

Dissecting the regulatory architecture of gene expression QTLs
por: Gaffney, Daniel J, et al.
Publicado: (2012)

Exon-Specific QTLs Skew the Inferred Distribution of Expression QTLs Detected Using Gene Expression Array Data
por: Veyrieras, Jean-Baptiste, et al.
Publicado: (2012)

Correction: DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines
por: Bell, Jordana T, et al.
Publicado: (2011)

DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines
por: Bell, Jordana T, et al.
Publicado: (2011)

Epigenetic modifications are associated with inter-species gene expression variation in primates
por: Zhou, Xiang, et al.
Publicado: (2014)

Effect of read-mapping biases on detecting allele-specific expression from RNA-sequencing data
por: Degner, Jacob F., et al.
Publicado: (2009)

Noisy Splicing Drives mRNA Isoform Diversity in Human Cells
por: Pickrell, Joseph K., et al.
Publicado: (2010)

Controls of Nucleosome Positioning in the Human Genome
por: Gaffney, Daniel J., et al.
Publicado: (2012)

The Genetic and Mechanistic Basis for Variation in Gene Regulation
por: Pai, Athma A., et al.
Publicado: (2015)

False positive peaks in ChIP-seq and other sequencing-based functional assays caused by unannotated high copy number regions
por: Pickrell, Joseph K., et al.
Publicado: (2011)

High-Resolution Mapping of Expression-QTLs Yields Insight into Human Gene Regulation
por: Veyrieras, Jean-Baptiste, et al.
Publicado: (2008)

A Genome-Wide Study of DNA Methylation Patterns and Gene Expression Levels in Multiple Human and Chimpanzee Tissues
por: Pai, Athma A., et al.
Publicado: (2011)

A reanalysis of mouse ENCODE comparative gene expression data
por: Gilad, Yoav, et al.
Publicado: (2015)

The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes
por: Cusanovich, Darren A., et al.
Publicado: (2012)

Taxonomic Classification of Bacterial 16S rRNA Genes Using Short Sequencing Reads: Evaluation of Effective Study Designs
por: Mizrahi-Man, Orna, et al.
Publicado: (2013)

RNA-seq: impact of RNA degradation on transcript quantification
por: Gallego Romero, Irene, et al.
Publicado: (2014)

msCentipede: Modeling Heterogeneity across Genomic Sites and Replicates Improves Accuracy in the Inference of Transcription Factor Binding
por: Raj, Anil, et al.
Publicado: (2015)

Seasonal Variation in Human Gut Microbiome Composition
por: Davenport, Emily R., et al.
Publicado: (2014)

Gene Expression Levels Are a Target of Recent Natural Selection in the Human Genome
por: Kudaravalli, Sridhar, et al.
Publicado: (2009)

Methylation QTLs Are Associated with Coordinated Changes in Transcription Factor Binding, Histone Modifications, and Gene Expression Levels
por: Banovich, Nicholas E., et al.
Publicado: (2014)

Inference of Population Splits and Mixtures from Genome-Wide Allele Frequency Data
por: Pickrell, Joseph K., et al.
Publicado: (2012)

The Effect of Freeze-Thaw Cycles on Gene Expression Levels in Lymphoblastoid Cell Lines
por: Çalışkan, Minal, et al.
Publicado: (2014)

The Functional Consequences of Variation in Transcription Factor Binding
por: Cusanovich, Darren A., et al.
Publicado: (2014)

Steady Beat Sound Facilitates both Coordinated Group Walking and Inter-Subject Neural Synchrony
por: Ikeda, Shigeyuki, et al.
Publicado: (2017)

Influence of inter-stimulus interval on 40-Hz auditory steady-state response in patients with schizophrenia
por: Choi, Kang-Min, et al.
Publicado: (2023)

MetaQTL: a package of new computational methods for the meta-analysis of QTL mapping experiments
por: Veyrieras, Jean-Baptiste, et al.
Publicado: (2007)

Construction of a potato consensus map and QTL meta-analysis offer new insights into the genetic architecture of late blight resistance and plant maturity traits
por: Danan, Sarah, et al.
Publicado: (2011)

Thousands of novel translated open reading frames in humans inferred by ribosome footprint profiling
por: Raj, Anil, et al.
Publicado: (2016)

Identification of quantitative trait loci for dynamic and steady-state photosynthetic traits in a barley mapping population
por: Salter, William T, et al.
Publicado: (2020)

WASP: allele-specific software for robust molecular quantitative trait locus discovery
por: van de Geijn, Bryce, et al.
Publicado: (2015)

Quantitative trait loci associated with short inter-node length in soybean
por: Oki, Nobuhiko, et al.
Publicado: (2018)

Quantitative trait loci associated with short inter-node length in soybean
por: Oki, Nobuhiko, et al.
Publicado: (2019)

A Framework for Exploring Functional Variability in Olfactory Receptor Genes
por: Man, Orna, et al.
Publicado: (2007)

Co-binding by YY1 identifies the transcriptionally active, highly conserved set of CTCF-bound regions in primate genomes
por: Schwalie, Petra C, et al.
Publicado: (2013)

Editorial: Alternative Polyadenylation in Development and Disease
por: Pai, Athma A., et al.
Publicado: (2022)

Challenges in identifying mRNA transcript starts and ends from long-read sequencing data
por: Calvo-Roitberg, Ezequiel, et al.
Publicado: (2023)

Steady flow, not steady state – a plea for physiological thinking
por: Nick, Peter
Publicado: (2021)

The association of clinical phenotypes to known AD/FTD genetic risk loci and their inter-relationship
por: Li, Qingqin S., et al.
Publicado: (2020)

Measurement of thermal sweating at rest and steady-state exercise in healthy adults: Inter-day reliability and relationships with components of partitional calorimetry
por: Peel, Jennifer S., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_01chsljq6ipo8fkl5k2hiiqhul