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Regulation of the human TRAIL gene

TRAIL is a member of the TNF superfamily that induces tumor-selective cell death by engaging the pro-apoptotic death receptors DR4 and DR5. The antitumor potential of the TRAIL pathway has been targeted by several therapeutic approaches including recombinant TRAIL and TRAIL-receptor agonist antibodi...

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Detalles Bibliográficos
Autores principales: Allen, Joshua E., El-Deiry, Wafik S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469471/
https://www.ncbi.nlm.nih.gov/pubmed/22892844
http://dx.doi.org/10.4161/cbt.21354