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Actin-capping protein promotes microtubule stability by antagonizing the actin activity of mDia1
In migrating fibroblasts, RhoA and its effector mDia1 regulate the selective stabilization of microtubules (MTs) polarized in the direction of migration. The conserved formin homology 2 domain of mDia1 is involved both in actin polymerization and MT stabilization, and the relationship between these...
Autores principales: | Bartolini, Francesca, Ramalingam, Nagendran, Gundersen, Gregg G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469518/ https://www.ncbi.nlm.nih.gov/pubmed/22918941 http://dx.doi.org/10.1091/mbc.E12-05-0338 |
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