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Actin-capping protein promotes microtubule stability by antagonizing the actin activity of mDia1

In migrating fibroblasts, RhoA and its effector mDia1 regulate the selective stabilization of microtubules (MTs) polarized in the direction of migration. The conserved formin homology 2 domain of mDia1 is involved both in actin polymerization and MT stabilization, and the relationship between these...

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Detalles Bibliográficos
Autores principales: Bartolini, Francesca, Ramalingam, Nagendran, Gundersen, Gregg G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469518/
https://www.ncbi.nlm.nih.gov/pubmed/22918941
http://dx.doi.org/10.1091/mbc.E12-05-0338

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