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Selective Decline of Synaptic Protein Levels in the Frontal Cortex of Female Mice Deficient in the Extracellular Metalloproteinase ADAMTS1

The chondroitin sulfate-bearing proteoglycans, also known as lecticans, are a major component of the extracellular matrix (ECM) in the central nervous system and regulate neural plasticity. Growing evidence indicates that endogenous, extracellular metalloproteinases that cleave lecticans mediate neu...

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Detalles Bibliográficos
Autores principales: Howell, Matthew D., Torres-Collado, Antoni X., Iruela-Arispe, M. Luisa, Gottschall, Paul E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469530/
https://www.ncbi.nlm.nih.gov/pubmed/23071766
http://dx.doi.org/10.1371/journal.pone.0047226