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MSM Enhances GH Signaling via the Jak2/STAT5b Pathway in Osteoblast-Like Cells and Osteoblast Differentiation through the Activation of STAT5b in MSCs
Methylsulfonylmethane (MSM) is a naturally occurring sulfur compound with well-known anti-oxidant properties and anti-inflammatory activities. But, its effects on bone are unknown. Growth hormone (GH) is regulator of bone growth and bone metabolism. GH activates several signaling pathways such as th...
Autores principales: | Joung, Youn Hee, Lim, Eun Joung, Darvin, Pramod, Chung, So Chung, Jang, Ju Woong, Do Park, Kyung, Lee, Hak Kyo, Kim, Heui Soo, Park, Taekyu, Yang, Young Mok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469535/ https://www.ncbi.nlm.nih.gov/pubmed/23071812 http://dx.doi.org/10.1371/journal.pone.0047477 |
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