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Small-Molecule Quinolinol Inhibitor Identified Provides Protection against BoNT/A in Mice

Botulinum neurotoxins (BoNTs), etiological agents of the life threatening neuroparalytic disease botulism, are the most toxic substances currently known. The potential for the use as bioweapon makes the development of small-molecule inhibitor against these deadly toxins is a top priority. Currently,...

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Detalles Bibliográficos
Autores principales: Singh, Padma, Singh, Manglesh Kumar, Chaudhary, Dilip, Chauhan, Vinita, Bharadwaj, Pranay, Pandey, Apurva, Upadhyay, Nisha, Dhaked, Ram Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469547/
https://www.ncbi.nlm.nih.gov/pubmed/23071727
http://dx.doi.org/10.1371/journal.pone.0047110