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Small-Molecule Quinolinol Inhibitor Identified Provides Protection against BoNT/A in Mice
Botulinum neurotoxins (BoNTs), etiological agents of the life threatening neuroparalytic disease botulism, are the most toxic substances currently known. The potential for the use as bioweapon makes the development of small-molecule inhibitor against these deadly toxins is a top priority. Currently,...
Autores principales: | Singh, Padma, Singh, Manglesh Kumar, Chaudhary, Dilip, Chauhan, Vinita, Bharadwaj, Pranay, Pandey, Apurva, Upadhyay, Nisha, Dhaked, Ram Kumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469547/ https://www.ncbi.nlm.nih.gov/pubmed/23071727 http://dx.doi.org/10.1371/journal.pone.0047110 |
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