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Immunogenicity and Efficacy of Intramuscular Replication-Defective and Subunit Vaccines against Herpes Simplex Virus Type 2 in the Mouse Genital Model

Herpes simplex virus type 2 (HSV-2) is a sexually transmitted virus that is highly prevalent worldwide, causing a range of symptoms that result in significant healthcare costs and human suffering. ACAM529 is a replication-defective vaccine candidate prepared by growing the previously described dl5-2...

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Detalles Bibliográficos
Autores principales:	Delagrave, Simon, Hernandez, Hector, Zhou, Changhong, Hamberger, John F., Mundle, Sophia T., Catalan, John, Baloglu, Simge, Anderson, Stephen F., DiNapoli, Joshua M., Londoño-Hayes, Patricia, Parrington, Mark, Almond, Jeffrey, Kleanthous, Harry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469653/ https://www.ncbi.nlm.nih.gov/pubmed/23071620 http://dx.doi.org/10.1371/journal.pone.0046714

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