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Scavenger Receptor Class A Plays a Central Role in Mediating Mortality and the Development of the Pro-Inflammatory Phenotype in Polymicrobial Sepsis

Sepsis is a frequent complication in critical illness. The mechanisms that are involved in initiation and propagation of the disease are not well understood. Scavenger receptor A (SRA) is a membrane receptor that binds multiple polyanions such as oxidized LDL and endotoxin. Recent studies suggest th...

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Detalles Bibliográficos
Autores principales: Ozment, Tammy R., Ha, Tuanzhu, Breuel, Kevin F., Ford, Tiffany R., Ferguson, Donald A., Kalbfleisch, John, Schweitzer, John B., Kelley, Jim L., Li, Chuanfu, Williams, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469655/
https://www.ncbi.nlm.nih.gov/pubmed/23071440
http://dx.doi.org/10.1371/journal.ppat.1002967