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Scavenger Receptor Class A Plays a Central Role in Mediating Mortality and the Development of the Pro-Inflammatory Phenotype in Polymicrobial Sepsis
Sepsis is a frequent complication in critical illness. The mechanisms that are involved in initiation and propagation of the disease are not well understood. Scavenger receptor A (SRA) is a membrane receptor that binds multiple polyanions such as oxidized LDL and endotoxin. Recent studies suggest th...
Autores principales: | Ozment, Tammy R., Ha, Tuanzhu, Breuel, Kevin F., Ford, Tiffany R., Ferguson, Donald A., Kalbfleisch, John, Schweitzer, John B., Kelley, Jim L., Li, Chuanfu, Williams, David L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469655/ https://www.ncbi.nlm.nih.gov/pubmed/23071440 http://dx.doi.org/10.1371/journal.ppat.1002967 |
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