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Extended coherence length megahertz FDML and its application for anterior segment imaging

We present a 1300 nm Fourier domain mode locked (FDML) laser for optical coherence tomography (OCT) that combines both, a high 1.6 MHz wavelength sweep rate and an ultra-long instantaneous coherence length for rapid volumetric deep field imaging. By reducing the dispersion in the fiber delay line of...

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Autores principales: Wieser, Wolfgang, Klein, Thomas, Adler, Desmond C., Trépanier, Francois, Eigenwillig, Christoph M., Karpf, Sebastian, Schmitt, Joseph M., Huber, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470011/
https://www.ncbi.nlm.nih.gov/pubmed/23082303
http://dx.doi.org/10.1364/BOE.3.002647
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author Wieser, Wolfgang
Klein, Thomas
Adler, Desmond C.
Trépanier, Francois
Eigenwillig, Christoph M.
Karpf, Sebastian
Schmitt, Joseph M.
Huber, Robert
author_facet Wieser, Wolfgang
Klein, Thomas
Adler, Desmond C.
Trépanier, Francois
Eigenwillig, Christoph M.
Karpf, Sebastian
Schmitt, Joseph M.
Huber, Robert
author_sort Wieser, Wolfgang
collection PubMed
description We present a 1300 nm Fourier domain mode locked (FDML) laser for optical coherence tomography (OCT) that combines both, a high 1.6 MHz wavelength sweep rate and an ultra-long instantaneous coherence length for rapid volumetric deep field imaging. By reducing the dispersion in the fiber delay line of the FDML laser, the instantaneous coherence length and hence the available imaging range is approximately quadrupled compared to previously published MHz-FDML setups, the imaging speed is increased by a factor of 16 compared to previous extended coherence length results. We present a detailed characterization of the FDML laser performance. We demonstrate for the first time MHz-OCT imaging of the anterior segment of the human eye. The OCT system provides enough imaging depth to cover the whole range from the top surface of the cornea down to the crystalline lens.
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spelling pubmed-34700112012-10-18 Extended coherence length megahertz FDML and its application for anterior segment imaging Wieser, Wolfgang Klein, Thomas Adler, Desmond C. Trépanier, Francois Eigenwillig, Christoph M. Karpf, Sebastian Schmitt, Joseph M. Huber, Robert Biomed Opt Express Optical Coherence Tomography We present a 1300 nm Fourier domain mode locked (FDML) laser for optical coherence tomography (OCT) that combines both, a high 1.6 MHz wavelength sweep rate and an ultra-long instantaneous coherence length for rapid volumetric deep field imaging. By reducing the dispersion in the fiber delay line of the FDML laser, the instantaneous coherence length and hence the available imaging range is approximately quadrupled compared to previously published MHz-FDML setups, the imaging speed is increased by a factor of 16 compared to previous extended coherence length results. We present a detailed characterization of the FDML laser performance. We demonstrate for the first time MHz-OCT imaging of the anterior segment of the human eye. The OCT system provides enough imaging depth to cover the whole range from the top surface of the cornea down to the crystalline lens. Optical Society of America 2012-09-24 /pmc/articles/PMC3470011/ /pubmed/23082303 http://dx.doi.org/10.1364/BOE.3.002647 Text en ©2012 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.
spellingShingle Optical Coherence Tomography
Wieser, Wolfgang
Klein, Thomas
Adler, Desmond C.
Trépanier, Francois
Eigenwillig, Christoph M.
Karpf, Sebastian
Schmitt, Joseph M.
Huber, Robert
Extended coherence length megahertz FDML and its application for anterior segment imaging
title Extended coherence length megahertz FDML and its application for anterior segment imaging
title_full Extended coherence length megahertz FDML and its application for anterior segment imaging
title_fullStr Extended coherence length megahertz FDML and its application for anterior segment imaging
title_full_unstemmed Extended coherence length megahertz FDML and its application for anterior segment imaging
title_short Extended coherence length megahertz FDML and its application for anterior segment imaging
title_sort extended coherence length megahertz fdml and its application for anterior segment imaging
topic Optical Coherence Tomography
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470011/
https://www.ncbi.nlm.nih.gov/pubmed/23082303
http://dx.doi.org/10.1364/BOE.3.002647
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