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5-(4-Fluorobenzylidene)-4′-(4-fluorophenyl)-1,1′-dimethyldispiro[piperidine-3,3′-pyrrolidine-2′,3′′-indoline]-4,2′′-dione
The asymmetric unit of the title compound, C(30)H(27)F(2)N(3)O(2), contains two independent molecules. The pyrrolidine five-membered ring assumes an envelope conformation (with the CH(2) atom at the flap) in one molecule and a twisted conformation in the other one. In both independent molecules,...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470200/ https://www.ncbi.nlm.nih.gov/pubmed/23125644 http://dx.doi.org/10.1107/S1600536812037245 |
| _version_ | 1782246218323197952 |
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| author | Swamy, V. Rajni Ramaswamy, S. Srinivasan, N. Kumar, R. Ranjith Krishnakumar, R.V. |
| author_facet | Swamy, V. Rajni Ramaswamy, S. Srinivasan, N. Kumar, R. Ranjith Krishnakumar, R.V. |
| author_sort | Swamy, V. Rajni |
| collection | PubMed |
| description | The asymmetric unit of the title compound, C(30)H(27)F(2)N(3)O(2), contains two independent molecules. The pyrrolidine five-membered ring assumes an envelope conformation (with the CH(2) atom at the flap) in one molecule and a twisted conformation in the other one. In both independent molecules, the 4-piperidinone rings adopt a similar twisted chair conformation. In the crystal, the two independent molecules form an R (2) (2)(8) dimer through a pair of N—H⋯O hydrogen bonds; the R (2) (2)(8) dimers are connected via weak C—H⋯O hydrogen bonds, leading to a chain extending along the c axis. |
| format | Online Article Text |
| id | pubmed-3470200 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2012 |
| publisher | International Union of Crystallography |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-34702002012-11-02 5-(4-Fluorobenzylidene)-4′-(4-fluorophenyl)-1,1′-dimethyldispiro[piperidine-3,3′-pyrrolidine-2′,3′′-indoline]-4,2′′-dione Swamy, V. Rajni Ramaswamy, S. Srinivasan, N. Kumar, R. Ranjith Krishnakumar, R.V. Acta Crystallogr Sect E Struct Rep Online Organic Papers The asymmetric unit of the title compound, C(30)H(27)F(2)N(3)O(2), contains two independent molecules. The pyrrolidine five-membered ring assumes an envelope conformation (with the CH(2) atom at the flap) in one molecule and a twisted conformation in the other one. In both independent molecules, the 4-piperidinone rings adopt a similar twisted chair conformation. In the crystal, the two independent molecules form an R (2) (2)(8) dimer through a pair of N—H⋯O hydrogen bonds; the R (2) (2)(8) dimers are connected via weak C—H⋯O hydrogen bonds, leading to a chain extending along the c axis. International Union of Crystallography 2012-09-05 /pmc/articles/PMC3470200/ /pubmed/23125644 http://dx.doi.org/10.1107/S1600536812037245 Text en © Swamy et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
| spellingShingle | Organic Papers Swamy, V. Rajni Ramaswamy, S. Srinivasan, N. Kumar, R. Ranjith Krishnakumar, R.V. 5-(4-Fluorobenzylidene)-4′-(4-fluorophenyl)-1,1′-dimethyldispiro[piperidine-3,3′-pyrrolidine-2′,3′′-indoline]-4,2′′-dione |
| title | 5-(4-Fluorobenzylidene)-4′-(4-fluorophenyl)-1,1′-dimethyldispiro[piperidine-3,3′-pyrrolidine-2′,3′′-indoline]-4,2′′-dione |
| title_full | 5-(4-Fluorobenzylidene)-4′-(4-fluorophenyl)-1,1′-dimethyldispiro[piperidine-3,3′-pyrrolidine-2′,3′′-indoline]-4,2′′-dione |
| title_fullStr | 5-(4-Fluorobenzylidene)-4′-(4-fluorophenyl)-1,1′-dimethyldispiro[piperidine-3,3′-pyrrolidine-2′,3′′-indoline]-4,2′′-dione |
| title_full_unstemmed | 5-(4-Fluorobenzylidene)-4′-(4-fluorophenyl)-1,1′-dimethyldispiro[piperidine-3,3′-pyrrolidine-2′,3′′-indoline]-4,2′′-dione |
| title_short | 5-(4-Fluorobenzylidene)-4′-(4-fluorophenyl)-1,1′-dimethyldispiro[piperidine-3,3′-pyrrolidine-2′,3′′-indoline]-4,2′′-dione |
| title_sort | 5-(4-fluorobenzylidene)-4′-(4-fluorophenyl)-1,1′-dimethyldispiro[piperidine-3,3′-pyrrolidine-2′,3′′-indoline]-4,2′′-dione |
| topic | Organic Papers |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470200/ https://www.ncbi.nlm.nih.gov/pubmed/23125644 http://dx.doi.org/10.1107/S1600536812037245 |
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