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Methyl (3S,3′R)-1-methyl-2,2′′-dioxo-1′,2′,3′,5′,6′,7′,8′,8a′-octahydrodispiro[indoline-3,2′-indolizine-3′,3′′-indoline]-1′-carboxylate
In the title compound, C(25)H(25)N(3)O(4), the central pyrrolidine ring and the two pyrrolidine rings adopt twisted conformations, whereas the piperidine ring in the octahydroindolizine fused ring system adopts a chair conformation. The indoline ring systems are almost perpendicular with respect t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470251/ https://www.ncbi.nlm.nih.gov/pubmed/23125695 http://dx.doi.org/10.1107/S1600536812037531 |
Sumario: | In the title compound, C(25)H(25)N(3)O(4), the central pyrrolidine ring and the two pyrrolidine rings adopt twisted conformations, whereas the piperidine ring in the octahydroindolizine fused ring system adopts a chair conformation. The indoline ring systems are almost perpendicular with respect to the mean plane of the octahydroindolizine ring system, making dihedral angles of 84.4 (5) and 79.4 (5)°. The acetate group attached to the octahydroindolizine ring system assumes an extended conformation. In the crystal, N—H⋯O hydrogen bonds result in the formation of a helical C(7) chain running parallel to [101]. The crystal packing features C—H⋯O hydrogen bonds and C—H⋯π interactions. |
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