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Methyl (3S,3′R)-1-methyl-2,2′′-dioxo-1′,2′,3′,5′,6′,7′,8′,8a′-octahydrodispiro[indoline-3,2′-indolizine-3′,3′′-indoline]-1′-carboxylate
In the title compound, C(25)H(25)N(3)O(4), the central pyrrolidine ring and the two pyrrolidine rings adopt twisted conformations, whereas the piperidine ring in the octahydroindolizine fused ring system adopts a chair conformation. The indoline ring systems are almost perpendicular with respect t...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470251/ https://www.ncbi.nlm.nih.gov/pubmed/23125695 http://dx.doi.org/10.1107/S1600536812037531 |
| _version_ | 1782246230110240768 |
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| author | Ganesh, G. Yuvaraj, Panneer Selvam Govindan, E. Reddy, Boreddy S. R. SubbiahPandi, A. |
| author_facet | Ganesh, G. Yuvaraj, Panneer Selvam Govindan, E. Reddy, Boreddy S. R. SubbiahPandi, A. |
| author_sort | Ganesh, G. |
| collection | PubMed |
| description | In the title compound, C(25)H(25)N(3)O(4), the central pyrrolidine ring and the two pyrrolidine rings adopt twisted conformations, whereas the piperidine ring in the octahydroindolizine fused ring system adopts a chair conformation. The indoline ring systems are almost perpendicular with respect to the mean plane of the octahydroindolizine ring system, making dihedral angles of 84.4 (5) and 79.4 (5)°. The acetate group attached to the octahydroindolizine ring system assumes an extended conformation. In the crystal, N—H⋯O hydrogen bonds result in the formation of a helical C(7) chain running parallel to [101]. The crystal packing features C—H⋯O hydrogen bonds and C—H⋯π interactions. |
| format | Online Article Text |
| id | pubmed-3470251 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2012 |
| publisher | International Union of Crystallography |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-34702512012-11-02 Methyl (3S,3′R)-1-methyl-2,2′′-dioxo-1′,2′,3′,5′,6′,7′,8′,8a′-octahydrodispiro[indoline-3,2′-indolizine-3′,3′′-indoline]-1′-carboxylate Ganesh, G. Yuvaraj, Panneer Selvam Govindan, E. Reddy, Boreddy S. R. SubbiahPandi, A. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(25)H(25)N(3)O(4), the central pyrrolidine ring and the two pyrrolidine rings adopt twisted conformations, whereas the piperidine ring in the octahydroindolizine fused ring system adopts a chair conformation. The indoline ring systems are almost perpendicular with respect to the mean plane of the octahydroindolizine ring system, making dihedral angles of 84.4 (5) and 79.4 (5)°. The acetate group attached to the octahydroindolizine ring system assumes an extended conformation. In the crystal, N—H⋯O hydrogen bonds result in the formation of a helical C(7) chain running parallel to [101]. The crystal packing features C—H⋯O hydrogen bonds and C—H⋯π interactions. International Union of Crystallography 2012-09-08 /pmc/articles/PMC3470251/ /pubmed/23125695 http://dx.doi.org/10.1107/S1600536812037531 Text en © Ganesh et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
| spellingShingle | Organic Papers Ganesh, G. Yuvaraj, Panneer Selvam Govindan, E. Reddy, Boreddy S. R. SubbiahPandi, A. Methyl (3S,3′R)-1-methyl-2,2′′-dioxo-1′,2′,3′,5′,6′,7′,8′,8a′-octahydrodispiro[indoline-3,2′-indolizine-3′,3′′-indoline]-1′-carboxylate |
| title | Methyl (3S,3′R)-1-methyl-2,2′′-dioxo-1′,2′,3′,5′,6′,7′,8′,8a′-octahydrodispiro[indoline-3,2′-indolizine-3′,3′′-indoline]-1′-carboxylate |
| title_full | Methyl (3S,3′R)-1-methyl-2,2′′-dioxo-1′,2′,3′,5′,6′,7′,8′,8a′-octahydrodispiro[indoline-3,2′-indolizine-3′,3′′-indoline]-1′-carboxylate |
| title_fullStr | Methyl (3S,3′R)-1-methyl-2,2′′-dioxo-1′,2′,3′,5′,6′,7′,8′,8a′-octahydrodispiro[indoline-3,2′-indolizine-3′,3′′-indoline]-1′-carboxylate |
| title_full_unstemmed | Methyl (3S,3′R)-1-methyl-2,2′′-dioxo-1′,2′,3′,5′,6′,7′,8′,8a′-octahydrodispiro[indoline-3,2′-indolizine-3′,3′′-indoline]-1′-carboxylate |
| title_short | Methyl (3S,3′R)-1-methyl-2,2′′-dioxo-1′,2′,3′,5′,6′,7′,8′,8a′-octahydrodispiro[indoline-3,2′-indolizine-3′,3′′-indoline]-1′-carboxylate |
| title_sort | methyl (3s,3′r)-1-methyl-2,2′′-dioxo-1′,2′,3′,5′,6′,7′,8′,8a′-octahydrodispiro[indoline-3,2′-indolizine-3′,3′′-indoline]-1′-carboxylate |
| topic | Organic Papers |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470251/ https://www.ncbi.nlm.nih.gov/pubmed/23125695 http://dx.doi.org/10.1107/S1600536812037531 |
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