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3-(2-Chloro-3-hydroxy-4-methoxyphenyl)-1-(4,5-dimethoxy-2-methylphenyl)prop-2-en-1-one
The title compound, C(19)H(19)ClO(5), is a chloro derivative of a biologically significant chalcone family. The mean plane of the two substituted benzene rings are twisted by 55.33 (8)° with respect to each other. An intramolecular C—H⋯Cl hydrogen bond generates an S(5) graph-set motif. In the crys...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470302/ https://www.ncbi.nlm.nih.gov/pubmed/23125715 http://dx.doi.org/10.1107/S1600536812038275 |
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author | Patel, U. H. Gandhi, S. A. Barot, V. M. Patel, M. C. |
author_facet | Patel, U. H. Gandhi, S. A. Barot, V. M. Patel, M. C. |
author_sort | Patel, U. H. |
collection | PubMed |
description | The title compound, C(19)H(19)ClO(5), is a chloro derivative of a biologically significant chalcone family. The mean plane of the two substituted benzene rings are twisted by 55.33 (8)° with respect to each other. An intramolecular C—H⋯Cl hydrogen bond generates an S(5) graph-set motif. In the crystal, a bifurcated O—H⋯(O,O) hydrogen bond leads to an R (1) (2)(5) graph-set motif and to the formation of zigzag chains propagating along the c-axis direction. A weak π–π interaction involving the methylphenyl rings [centroid–centroid distance = 3.8185 (10) Å] and C—H⋯π interactions also occur. |
format | Online Article Text |
id | pubmed-3470302 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-34703022012-11-02 3-(2-Chloro-3-hydroxy-4-methoxyphenyl)-1-(4,5-dimethoxy-2-methylphenyl)prop-2-en-1-one Patel, U. H. Gandhi, S. A. Barot, V. M. Patel, M. C. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(19)H(19)ClO(5), is a chloro derivative of a biologically significant chalcone family. The mean plane of the two substituted benzene rings are twisted by 55.33 (8)° with respect to each other. An intramolecular C—H⋯Cl hydrogen bond generates an S(5) graph-set motif. In the crystal, a bifurcated O—H⋯(O,O) hydrogen bond leads to an R (1) (2)(5) graph-set motif and to the formation of zigzag chains propagating along the c-axis direction. A weak π–π interaction involving the methylphenyl rings [centroid–centroid distance = 3.8185 (10) Å] and C—H⋯π interactions also occur. International Union of Crystallography 2012-09-12 /pmc/articles/PMC3470302/ /pubmed/23125715 http://dx.doi.org/10.1107/S1600536812038275 Text en © Patel et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Patel, U. H. Gandhi, S. A. Barot, V. M. Patel, M. C. 3-(2-Chloro-3-hydroxy-4-methoxyphenyl)-1-(4,5-dimethoxy-2-methylphenyl)prop-2-en-1-one |
title | 3-(2-Chloro-3-hydroxy-4-methoxyphenyl)-1-(4,5-dimethoxy-2-methylphenyl)prop-2-en-1-one |
title_full | 3-(2-Chloro-3-hydroxy-4-methoxyphenyl)-1-(4,5-dimethoxy-2-methylphenyl)prop-2-en-1-one |
title_fullStr | 3-(2-Chloro-3-hydroxy-4-methoxyphenyl)-1-(4,5-dimethoxy-2-methylphenyl)prop-2-en-1-one |
title_full_unstemmed | 3-(2-Chloro-3-hydroxy-4-methoxyphenyl)-1-(4,5-dimethoxy-2-methylphenyl)prop-2-en-1-one |
title_short | 3-(2-Chloro-3-hydroxy-4-methoxyphenyl)-1-(4,5-dimethoxy-2-methylphenyl)prop-2-en-1-one |
title_sort | 3-(2-chloro-3-hydroxy-4-methoxyphenyl)-1-(4,5-dimethoxy-2-methylphenyl)prop-2-en-1-one |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470302/ https://www.ncbi.nlm.nih.gov/pubmed/23125715 http://dx.doi.org/10.1107/S1600536812038275 |
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