4-Acetyl-1H-pyrrole-2-carbaldehyde

The title compound, C(7)H(7)NO(2), was synthesized via a one-pot Vilsmeier–Haack and subsequent Friedel–Crafts reaction. The pyrazole ring makes dihedral angles of 4.50 (9) and 2.06 (8)°, respectively, with the aldehyde and acetyl groups. In the crystal, classical N—H⋯O hydrogen bonds and weak C—H⋯O...

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Autores principales: Sun, Tao, Xie, Jia-Wei, Zhao, Ren-Ying, Zhu, Ai-Guo, Ge, Yan-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470319/
https://www.ncbi.nlm.nih.gov/pubmed/23125732
http://dx.doi.org/10.1107/S1600536812039153
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author Sun, Tao
Xie, Jia-Wei
Zhao, Ren-Ying
Zhu, Ai-Guo
Ge, Yan-Qing
author_facet Sun, Tao
Xie, Jia-Wei
Zhao, Ren-Ying
Zhu, Ai-Guo
Ge, Yan-Qing
author_sort Sun, Tao
collection PubMed
description The title compound, C(7)H(7)NO(2), was synthesized via a one-pot Vilsmeier–Haack and subsequent Friedel–Crafts reaction. The pyrazole ring makes dihedral angles of 4.50 (9) and 2.06 (8)°, respectively, with the aldehyde and acetyl groups. In the crystal, classical N—H⋯O hydrogen bonds and weak C—H⋯O inter­actions assemble the mol­ecules into a chain along the b axis.
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spelling pubmed-34703192012-11-02 4-Acetyl-1H-pyrrole-2-carbaldehyde Sun, Tao Xie, Jia-Wei Zhao, Ren-Ying Zhu, Ai-Guo Ge, Yan-Qing Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(7)H(7)NO(2), was synthesized via a one-pot Vilsmeier–Haack and subsequent Friedel–Crafts reaction. The pyrazole ring makes dihedral angles of 4.50 (9) and 2.06 (8)°, respectively, with the aldehyde and acetyl groups. In the crystal, classical N—H⋯O hydrogen bonds and weak C—H⋯O inter­actions assemble the mol­ecules into a chain along the b axis. International Union of Crystallography 2012-09-19 /pmc/articles/PMC3470319/ /pubmed/23125732 http://dx.doi.org/10.1107/S1600536812039153 Text en © Sun et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Sun, Tao
Xie, Jia-Wei
Zhao, Ren-Ying
Zhu, Ai-Guo
Ge, Yan-Qing
4-Acetyl-1H-pyrrole-2-carbaldehyde
title 4-Acetyl-1H-pyrrole-2-carbaldehyde
title_full 4-Acetyl-1H-pyrrole-2-carbaldehyde
title_fullStr 4-Acetyl-1H-pyrrole-2-carbaldehyde
title_full_unstemmed 4-Acetyl-1H-pyrrole-2-carbaldehyde
title_short 4-Acetyl-1H-pyrrole-2-carbaldehyde
title_sort 4-acetyl-1h-pyrrole-2-carbaldehyde
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470319/
https://www.ncbi.nlm.nih.gov/pubmed/23125732
http://dx.doi.org/10.1107/S1600536812039153
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AT geyanqing 4acetyl1hpyrrole2carbaldehyde

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