Cargando…

5-Chloro-N-{4-oxo-2-[4-(trifluoro­meth­yl)phen­yl]-1,3-thia­zolidin-3-yl}-3-phenyl-1H-indole-2-carboxamide

In the title compound, C(25)H(17)ClF(3)N(3)O(2)S, the five-membered 1,3-thia­zolidine ring adopts a twist conformation. The three F atoms of the CF(3) group are disordered over two sets of sites with refined occupancies of 0.542 (18) and 0.458 (18). In the nine-membered 1H-indoline ring system, the...

Descripción completa

Detalles Bibliográficos
Autores principales: Akkurt, Mehmet, Çelik, İsmail, Gürbüzel, Füsun Kazan, Özkırımlı, Sumru, Büyükgüngör, Orhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470337/
https://www.ncbi.nlm.nih.gov/pubmed/23125750
http://dx.doi.org/10.1107/S1600536812039347
_version_ 1782246253767163904
author Akkurt, Mehmet
Çelik, İsmail
Gürbüzel, Füsun Kazan
Özkırımlı, Sumru
Büyükgüngör, Orhan
author_facet Akkurt, Mehmet
Çelik, İsmail
Gürbüzel, Füsun Kazan
Özkırımlı, Sumru
Büyükgüngör, Orhan
author_sort Akkurt, Mehmet
collection PubMed
description In the title compound, C(25)H(17)ClF(3)N(3)O(2)S, the five-membered 1,3-thia­zolidine ring adopts a twist conformation. The three F atoms of the CF(3) group are disordered over two sets of sites with refined occupancies of 0.542 (18) and 0.458 (18). In the nine-membered 1H-indoline ring system, the 1H-pyrrole ring forms a dihedral angle of 4.7 (2)° with the benzene ring, while it is twisted at an angle of 46.5 (2)° with respect to the attached phenyl ring. The dihedral angle between the phenyl and trifluoro­methyl-substituted benzene rings is 56.0 (2)°. In the crystal, N—H⋯O hydrogen bonds connect the mol­ecules into a three-dimensional network. In addition, weak C—H⋯O hydrogen bonds and weak C—H⋯π inter­actions are observed.
format Online
Article
Text
id pubmed-3470337
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-34703372012-11-02 5-Chloro-N-{4-oxo-2-[4-(trifluoro­meth­yl)phen­yl]-1,3-thia­zolidin-3-yl}-3-phenyl-1H-indole-2-carboxamide Akkurt, Mehmet Çelik, İsmail Gürbüzel, Füsun Kazan Özkırımlı, Sumru Büyükgüngör, Orhan Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(25)H(17)ClF(3)N(3)O(2)S, the five-membered 1,3-thia­zolidine ring adopts a twist conformation. The three F atoms of the CF(3) group are disordered over two sets of sites with refined occupancies of 0.542 (18) and 0.458 (18). In the nine-membered 1H-indoline ring system, the 1H-pyrrole ring forms a dihedral angle of 4.7 (2)° with the benzene ring, while it is twisted at an angle of 46.5 (2)° with respect to the attached phenyl ring. The dihedral angle between the phenyl and trifluoro­methyl-substituted benzene rings is 56.0 (2)°. In the crystal, N—H⋯O hydrogen bonds connect the mol­ecules into a three-dimensional network. In addition, weak C—H⋯O hydrogen bonds and weak C—H⋯π inter­actions are observed. International Union of Crystallography 2012-09-22 /pmc/articles/PMC3470337/ /pubmed/23125750 http://dx.doi.org/10.1107/S1600536812039347 Text en © Akkurt et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Akkurt, Mehmet
Çelik, İsmail
Gürbüzel, Füsun Kazan
Özkırımlı, Sumru
Büyükgüngör, Orhan
5-Chloro-N-{4-oxo-2-[4-(trifluoro­meth­yl)phen­yl]-1,3-thia­zolidin-3-yl}-3-phenyl-1H-indole-2-carboxamide
title 5-Chloro-N-{4-oxo-2-[4-(trifluoro­meth­yl)phen­yl]-1,3-thia­zolidin-3-yl}-3-phenyl-1H-indole-2-carboxamide
title_full 5-Chloro-N-{4-oxo-2-[4-(trifluoro­meth­yl)phen­yl]-1,3-thia­zolidin-3-yl}-3-phenyl-1H-indole-2-carboxamide
title_fullStr 5-Chloro-N-{4-oxo-2-[4-(trifluoro­meth­yl)phen­yl]-1,3-thia­zolidin-3-yl}-3-phenyl-1H-indole-2-carboxamide
title_full_unstemmed 5-Chloro-N-{4-oxo-2-[4-(trifluoro­meth­yl)phen­yl]-1,3-thia­zolidin-3-yl}-3-phenyl-1H-indole-2-carboxamide
title_short 5-Chloro-N-{4-oxo-2-[4-(trifluoro­meth­yl)phen­yl]-1,3-thia­zolidin-3-yl}-3-phenyl-1H-indole-2-carboxamide
title_sort 5-chloro-n-{4-oxo-2-[4-(trifluoro­meth­yl)phen­yl]-1,3-thia­zolidin-3-yl}-3-phenyl-1h-indole-2-carboxamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470337/
https://www.ncbi.nlm.nih.gov/pubmed/23125750
http://dx.doi.org/10.1107/S1600536812039347
work_keys_str_mv AT akkurtmehmet 5chloron4oxo24trifluoromethylphenyl13thiazolidin3yl3phenyl1hindole2carboxamide
AT celikismail 5chloron4oxo24trifluoromethylphenyl13thiazolidin3yl3phenyl1hindole2carboxamide
AT gurbuzelfusunkazan 5chloron4oxo24trifluoromethylphenyl13thiazolidin3yl3phenyl1hindole2carboxamide
AT ozkırımlısumru 5chloron4oxo24trifluoromethylphenyl13thiazolidin3yl3phenyl1hindole2carboxamide
AT buyukgungororhan 5chloron4oxo24trifluoromethylphenyl13thiazolidin3yl3phenyl1hindole2carboxamide