Cargando…

rac-4-Chloro-2-[({2-[(3-chloro-6-hy­droxy-2,4-dimethyl­benz­yl)(meth­yl)amino]­prop­yl}(meth­yl)amino)­meth­yl]-3,5-dimethyl­phenol

The title compound, C(23)H(32)Cl(2)N(2)O(2), a potential chiral ligand for coordination chemistry, was prepared by a two-step reaction. The mol­ecule is located on a crystallographic centre of inversion. As a result, the methyl group bonded to the methyl­ene group is disordered over two equally occu...

Descripción completa

Detalles Bibliográficos
Autores principales: Rivera, Augusto, Pacheco, Dency José, Ríos-Motta, Jaime, Maldonado, Mauricio, Bolte, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470356/
https://www.ncbi.nlm.nih.gov/pubmed/23125769
http://dx.doi.org/10.1107/S1600536812039694
_version_ 1782246259326713856
author Rivera, Augusto
Pacheco, Dency José
Ríos-Motta, Jaime
Maldonado, Mauricio
Bolte, Michael
author_facet Rivera, Augusto
Pacheco, Dency José
Ríos-Motta, Jaime
Maldonado, Mauricio
Bolte, Michael
author_sort Rivera, Augusto
collection PubMed
description The title compound, C(23)H(32)Cl(2)N(2)O(2), a potential chiral ligand for coordination chemistry, was prepared by a two-step reaction. The mol­ecule is located on a crystallographic centre of inversion. As a result, the methyl group bonded to the methyl­ene group is disordered over two equally occupied positions, sharing the same site as the H atom of the chiral C atom. As a further consequence of the crystallographic centrosymmetry, the 1,2-diamino­propane unit adopts an anti­periplanar conformation and the two benzene rings are coplanar. The central chain is in an all-trans arrangement. An intra­molecular O—H⋯N hydrogen bond makes an S(6) ring motif. A C—H⋯π inter­action links the mol­ecules into one-dimensional chains along the [001] direction.
format Online
Article
Text
id pubmed-3470356
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-34703562012-11-02 rac-4-Chloro-2-[({2-[(3-chloro-6-hy­droxy-2,4-dimethyl­benz­yl)(meth­yl)amino]­prop­yl}(meth­yl)amino)­meth­yl]-3,5-dimethyl­phenol Rivera, Augusto Pacheco, Dency José Ríos-Motta, Jaime Maldonado, Mauricio Bolte, Michael Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(23)H(32)Cl(2)N(2)O(2), a potential chiral ligand for coordination chemistry, was prepared by a two-step reaction. The mol­ecule is located on a crystallographic centre of inversion. As a result, the methyl group bonded to the methyl­ene group is disordered over two equally occupied positions, sharing the same site as the H atom of the chiral C atom. As a further consequence of the crystallographic centrosymmetry, the 1,2-diamino­propane unit adopts an anti­periplanar conformation and the two benzene rings are coplanar. The central chain is in an all-trans arrangement. An intra­molecular O—H⋯N hydrogen bond makes an S(6) ring motif. A C—H⋯π inter­action links the mol­ecules into one-dimensional chains along the [001] direction. International Union of Crystallography 2012-09-26 /pmc/articles/PMC3470356/ /pubmed/23125769 http://dx.doi.org/10.1107/S1600536812039694 Text en © Rivera et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Rivera, Augusto
Pacheco, Dency José
Ríos-Motta, Jaime
Maldonado, Mauricio
Bolte, Michael
rac-4-Chloro-2-[({2-[(3-chloro-6-hy­droxy-2,4-dimethyl­benz­yl)(meth­yl)amino]­prop­yl}(meth­yl)amino)­meth­yl]-3,5-dimethyl­phenol
title rac-4-Chloro-2-[({2-[(3-chloro-6-hy­droxy-2,4-dimethyl­benz­yl)(meth­yl)amino]­prop­yl}(meth­yl)amino)­meth­yl]-3,5-dimethyl­phenol
title_full rac-4-Chloro-2-[({2-[(3-chloro-6-hy­droxy-2,4-dimethyl­benz­yl)(meth­yl)amino]­prop­yl}(meth­yl)amino)­meth­yl]-3,5-dimethyl­phenol
title_fullStr rac-4-Chloro-2-[({2-[(3-chloro-6-hy­droxy-2,4-dimethyl­benz­yl)(meth­yl)amino]­prop­yl}(meth­yl)amino)­meth­yl]-3,5-dimethyl­phenol
title_full_unstemmed rac-4-Chloro-2-[({2-[(3-chloro-6-hy­droxy-2,4-dimethyl­benz­yl)(meth­yl)amino]­prop­yl}(meth­yl)amino)­meth­yl]-3,5-dimethyl­phenol
title_short rac-4-Chloro-2-[({2-[(3-chloro-6-hy­droxy-2,4-dimethyl­benz­yl)(meth­yl)amino]­prop­yl}(meth­yl)amino)­meth­yl]-3,5-dimethyl­phenol
title_sort rac-4-chloro-2-[({2-[(3-chloro-6-hy­droxy-2,4-dimethyl­benz­yl)(meth­yl)amino]­prop­yl}(meth­yl)amino)­meth­yl]-3,5-dimethyl­phenol
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470356/
https://www.ncbi.nlm.nih.gov/pubmed/23125769
http://dx.doi.org/10.1107/S1600536812039694
work_keys_str_mv AT riveraaugusto rac4chloro223chloro6hydroxy24dimethylbenzylmethylaminopropylmethylaminomethyl35dimethylphenol
AT pachecodencyjose rac4chloro223chloro6hydroxy24dimethylbenzylmethylaminopropylmethylaminomethyl35dimethylphenol
AT riosmottajaime rac4chloro223chloro6hydroxy24dimethylbenzylmethylaminopropylmethylaminomethyl35dimethylphenol
AT maldonadomauricio rac4chloro223chloro6hydroxy24dimethylbenzylmethylaminopropylmethylaminomethyl35dimethylphenol
AT boltemichael rac4chloro223chloro6hydroxy24dimethylbenzylmethylaminopropylmethylaminomethyl35dimethylphenol