Propan-2-yl r-4-(4-fluoro­phen­yl)-3-hy­droxy-c-6-methyl-2-phenyl-4,5-dihydro-2H-indazole-t-5-carboxyl­ate

In the title compound, C(24)H(23)FN(2)O(3), the cyclo­hexene ring adopts a screw-boat conformation. The fluorobenzene ring attached to the cyclo­hexene ring and the phenyl ring attached to the indazole moiety are inclined to one another by 57.77 (13)°. In the crystal, mol­ecules are linked by O—H⋯N...

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Autores principales: Rizwana Begum, S., Hema, R., Pandiarajan, K., Balasubramanian, Sridhar, Anitha, A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470376/
https://www.ncbi.nlm.nih.gov/pubmed/23125789
http://dx.doi.org/10.1107/S1600536812039955
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author Rizwana Begum, S.
Hema, R.
Pandiarajan, K.
Balasubramanian, Sridhar
Anitha, A. G.
author_facet Rizwana Begum, S.
Hema, R.
Pandiarajan, K.
Balasubramanian, Sridhar
Anitha, A. G.
author_sort Rizwana Begum, S.
collection PubMed
description In the title compound, C(24)H(23)FN(2)O(3), the cyclo­hexene ring adopts a screw-boat conformation. The fluorobenzene ring attached to the cyclo­hexene ring and the phenyl ring attached to the indazole moiety are inclined to one another by 57.77 (13)°. In the crystal, mol­ecules are linked by O—H⋯N and C—H⋯O hydrogen bonds, forming chains with C(5) and C(10) graph-set motifs. There are also C—H⋯π inter­actions present. The isopropoxycarbonyl group undergoes considerable thermal motion.
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spelling pubmed-34703762012-11-02 Propan-2-yl r-4-(4-fluoro­phen­yl)-3-hy­droxy-c-6-methyl-2-phenyl-4,5-dihydro-2H-indazole-t-5-carboxyl­ate Rizwana Begum, S. Hema, R. Pandiarajan, K. Balasubramanian, Sridhar Anitha, A. G. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(24)H(23)FN(2)O(3), the cyclo­hexene ring adopts a screw-boat conformation. The fluorobenzene ring attached to the cyclo­hexene ring and the phenyl ring attached to the indazole moiety are inclined to one another by 57.77 (13)°. In the crystal, mol­ecules are linked by O—H⋯N and C—H⋯O hydrogen bonds, forming chains with C(5) and C(10) graph-set motifs. There are also C—H⋯π inter­actions present. The isopropoxycarbonyl group undergoes considerable thermal motion. International Union of Crystallography 2012-09-26 /pmc/articles/PMC3470376/ /pubmed/23125789 http://dx.doi.org/10.1107/S1600536812039955 Text en © Rizwana Begum et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Rizwana Begum, S.
Hema, R.
Pandiarajan, K.
Balasubramanian, Sridhar
Anitha, A. G.
Propan-2-yl r-4-(4-fluoro­phen­yl)-3-hy­droxy-c-6-methyl-2-phenyl-4,5-dihydro-2H-indazole-t-5-carboxyl­ate
title Propan-2-yl r-4-(4-fluoro­phen­yl)-3-hy­droxy-c-6-methyl-2-phenyl-4,5-dihydro-2H-indazole-t-5-carboxyl­ate
title_full Propan-2-yl r-4-(4-fluoro­phen­yl)-3-hy­droxy-c-6-methyl-2-phenyl-4,5-dihydro-2H-indazole-t-5-carboxyl­ate
title_fullStr Propan-2-yl r-4-(4-fluoro­phen­yl)-3-hy­droxy-c-6-methyl-2-phenyl-4,5-dihydro-2H-indazole-t-5-carboxyl­ate
title_full_unstemmed Propan-2-yl r-4-(4-fluoro­phen­yl)-3-hy­droxy-c-6-methyl-2-phenyl-4,5-dihydro-2H-indazole-t-5-carboxyl­ate
title_short Propan-2-yl r-4-(4-fluoro­phen­yl)-3-hy­droxy-c-6-methyl-2-phenyl-4,5-dihydro-2H-indazole-t-5-carboxyl­ate
title_sort propan-2-yl r-4-(4-fluoro­phen­yl)-3-hy­droxy-c-6-methyl-2-phenyl-4,5-dihydro-2h-indazole-t-5-carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470376/
https://www.ncbi.nlm.nih.gov/pubmed/23125789
http://dx.doi.org/10.1107/S1600536812039955
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