The unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis

The unfolded protein response (UPR) monitors the protein folding capacity of the endoplasmic reticulum (ER). In all organisms analyzed to date, the UPR drives transcriptional programs that allow cells to cope with ER stress. The non-conventional splicing of Hac1 (yeasts) and XBP1 (metazoans) mRNA, e...

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Detalles Bibliográficos
Autores principales: Kimmig, Philipp, Diaz, Marcy, Zheng, Jiashun, Williams, Christopher C, Lang, Alexander, Aragón, Tomas, Li, Hao, Walter, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2012
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470409/
https://www.ncbi.nlm.nih.gov/pubmed/23066505
http://dx.doi.org/10.7554/eLife.00048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470409/
https://www.ncbi.nlm.nih.gov/pubmed/23066505
http://dx.doi.org/10.7554/eLife.00048

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