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Notch Signalling Inhibits CD4 Expression during Initiation and Differentiation of Human T Cell Lineage

The Delta/Notch signal transduction pathway is central to T cell differentiation from haemopoietic stem cells (HSCs). Although T cell development is well characterized using expression of cell surface markers, the detailed mechanisms driving differentiation have not been established. This issue beco...

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Detalles Bibliográficos
Autores principales:	Carlin, Stephen M., Khoo, Melissa L. M., Ma, David D., Moore, John J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470571/ https://www.ncbi.nlm.nih.gov/pubmed/23071513 http://dx.doi.org/10.1371/journal.pone.0045342

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