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Terminal differentiation and loss of tumorigenicity of human cancers via pluripotency based reprogramming
Pluripotent cells can be derived from various types of somatic cells by nuclear reprogramming using defined transcription factors. It is however unclear whether human cancer cells can be similarly reprogrammed and subsequently terminally differentiated with abrogation of tumorigenicity. Here, using...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470785/ https://www.ncbi.nlm.nih.gov/pubmed/22777357 http://dx.doi.org/10.1038/onc.2012.237 |