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Regulation of Endocytic Clathrin Dynamics by Cargo Ubiquitination

Some endocytic cargoes control clathrin-coated pit (CCP) maturation, but it is not known how such regulation is communicated. We found that μ-opioid neuropeptide receptors signal to their enclosing CCPs by ubiquitination. Nonubiquitinated receptors delay CCPs at an intermediate stage of maturation,...

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Detalles Bibliográficos
Autores principales: Henry, Anastasia G., Hislop, James N., Grove, Joe, Thorn, Kurt, Marsh, Mark, von Zastrow, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470869/
https://www.ncbi.nlm.nih.gov/pubmed/22940114
http://dx.doi.org/10.1016/j.devcel.2012.08.003