Detection of ABCC1 expression in classical Hodgkin lymphoma is associated with increased risk of treatment failure using standard chemotherapy protocols

BACKGROUND: The mechanisms responsible for chemoresistance in patients with refractory classical Hodgkin lymphoma (CHL) are unknown. ATP-binding cassette (ABC) transporters confer multidrug resistance in various cancers and ABCC1 overexpression has been shown to contribute to drug resistance in the...

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Detalles Bibliográficos
Autores principales: Greaves, Wesley, Xiao, Lianchun, Sanchez-Espiridion, Beatriz, Kunkalla, Kranthi, Dave, Kunal S, Liang, Cynthia S, Singh, Rajesh R, Younes, Anas, Medeiros, L Jeffrey, Vega, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470996/
https://www.ncbi.nlm.nih.gov/pubmed/22871336
http://dx.doi.org/10.1186/1756-8722-5-47

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