Cargando…
More than insulator: multiple roles of CTCF at the H19-Igf2 imprinted domain
CTCF (CCCTC-binding factor)-mediated insulation at the H19-Insulin-like growth factor 2 (Igf2) imprinted domain is a classic example for imprinted gene regulation. DNA methylation difference in the imprinting control region (ICR) is inherited from the gametes and subsequently determines parental all...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471092/ https://www.ncbi.nlm.nih.gov/pubmed/23087708 http://dx.doi.org/10.3389/fgene.2012.00214 |