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More than insulator: multiple roles of CTCF at the H19-Igf2 imprinted domain

CTCF (CCCTC-binding factor)-mediated insulation at the H19-Insulin-like growth factor 2 (Igf2) imprinted domain is a classic example for imprinted gene regulation. DNA methylation difference in the imprinting control region (ICR) is inherited from the gametes and subsequently determines parental all...

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Detalles Bibliográficos
Autores principales:	Singh, Purnima, Lee, Dong-Hoon, Szabó, Piroska E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2012
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471092/ https://www.ncbi.nlm.nih.gov/pubmed/23087708 http://dx.doi.org/10.3389/fgene.2012.00214

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